GAD can have a significant effect on your daily life. However, many people develop GAD for no apparent reason. having a history of drug or alcohol misuse.having a painful long-term health condition, like arthritis.having a history of stressful or traumatic experiences, like domestic violence, child abuse or bullying.the genes you inherit from your parents – you’re estimated to be 5 times more likely to develop GAD if a close relative has it.an imbalance of the brain chemicals serotonin and noradrenaline, which are involved in the control and regulation of mood.overactivity in areas of the brain involved in emotions and behaviour.It’s likely that a combination of several factors plays a role, like: The exact cause of GAD is not fully understood. You may start to worry that there’ll be no solution. Not knowing what triggers your anxiety can intensify it. However, if you have GAD, it may not always be clear what you’re feeling anxious about. For example, if you have claustrophobia (a fear of enclosed spaces), you know that being confined in a small space will trigger your anxiety. If you’re anxious as a result of a specific phobia or because of panic disorder, you’ll usually know what the cause is. These actions can make you worry even more about yourself and increase your lack of self-esteem. You may also find going to work difficult and stressful and may take time off sick. Your symptoms may cause you to withdraw from social contact to avoid feelings of worry and dread.
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